LUPUS is an auto-immune disease, a type of self-allergy, whereby the patient's immune system createsantibodies which instead of protecting the body from bacteria, viruses and other foreign matter attack the person's own body tissues. The causes symptoms of extreme fatigue, joint pain, muscles aches, anaemia, general malaise, and can result in the destruction of vital organs. It is a disease with many manifestations, and each person's profile or list of symptoms may be different. LUPUS can mimic other diseases, such as Multiple Sclerosis and Rheumatoid Arthritis, making it difficukt to diagnose by GPs as they see few cases of LUPUS and thus are not alert to its possibility.

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Physicians are often cautious with their diagnosis as they do not want to label anyone until they are certain of LUPUS. Morerover, a careful review of the patients entire medical history is necessary, coupled with analysis of results obtained from tests relating to their immune status to provide accurate diagnosis. Currently there is no single test that can definitely say whether a person has LUPUS or not. Only be comprehensive examinationand consideration of symptoms and their history can a diagnosis be achieved.

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LUPUS is a complex disease in which almost every system in the body can be affected , and the diagnosis is based on a combination of symtoms, signs and test results. Once a diagnosis of LUPUS is made, the patients symptoms should be treated as necessary . The goal of the treatment is to control the symptoms and the disease so that the patient can lead as normal life as possible.

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Dr Graham R V Hughes MD FRCP

Consultant Rheumatologist.

St Thomas Hospital

London.+